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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASPM
All Species:
11.21
Human Site:
T246
Identified Species:
35.24
UniProt:
Q8IZT6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZT6
NP_060606.3
3477
409800
T246
L
S
V
R
R
S
T
T
Y
S
S
L
H
A
S
Chimpanzee
Pan troglodytes
P62293
3477
409724
T246
L
S
V
R
R
S
T
T
Y
S
S
L
H
A
S
Rhesus Macaque
Macaca mulatta
P62292
3479
410087
T246
L
S
V
R
R
S
T
T
Y
S
S
L
H
A
S
Dog
Lupus familis
XP_537130
3407
401187
T222
T
N
N
I
N
D
Q
T
E
E
N
C
K
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJ27
3122
364103
T145
K
K
R
S
L
W
N
T
S
K
K
I
P
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506218
2691
320176
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116845
3391
394231
L231
E
T
F
D
N
V
H
L
Q
K
D
S
P
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787918
3597
412342
F303
E
I
A
G
E
S
P
F
A
D
G
K
I
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.8
79.1
N.A.
63.2
N.A.
N.A.
50.1
N.A.
N.A.
39
N.A.
N.A.
N.A.
N.A.
31.4
Protein Similarity:
100
99.4
97.9
87.8
N.A.
74.8
N.A.
N.A.
63.5
N.A.
N.A.
59.9
N.A.
N.A.
N.A.
N.A.
53
P-Site Identity:
100
100
100
6.6
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
26.6
N.A.
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
13
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
13
0
13
0
0
0
13
13
0
0
0
0
% D
% Glu:
25
0
0
0
13
0
0
0
13
13
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
0
38
0
0
% H
% Ile:
0
13
0
13
0
0
0
0
0
0
0
13
13
0
13
% I
% Lys:
13
13
0
0
0
0
0
0
0
25
13
13
13
13
0
% K
% Leu:
38
0
0
0
13
0
0
13
0
0
0
38
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
13
0
25
0
13
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
13
38
38
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
38
0
13
0
50
0
0
13
38
38
13
0
0
50
% S
% Thr:
13
13
0
0
0
0
38
63
0
0
0
0
0
0
13
% T
% Val:
0
0
38
0
0
13
0
0
0
0
0
0
0
13
13
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _